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Despite these promising attributes, its essential to recognize that MK-677 is still undergoing scrutiny in clinical trials to evaluate its long-term safety and potential side effects

doi: 10.1016/j.nanoso.2023.101071 16 DongQ.LiZ.XuJ.YuanQ.ChenL.ChenZ

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Emodin ameliorates renal fibrosis in rats via TGF-1/Smad signaling pathway and function study of Smurf 2

This drug was shown to induce senescence both in vitro and in vivo in HCT116 models [80]