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5-Hydroxytryptophan and pyridoxine: their effects in young children with Downs syndrome

The liver uses glutathione for detoxification, but excessive consumption can overwhelm this process leading to depletion and increased oxidative stress

Antioxidants play a critical role in protecting liver cells, reducing inflammation, and preventing liver disease

This indicates that copper plays a crucial role in infant development: Copper imbalance driven by ATP7A mutations leads to extensive multi-organ dysfunction in MD, which is manifested as multi-system abnormalities and fatal outcomes in infants

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