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Nutr 13(3) Mokadem M et al (2014) Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency
The ice crystal formation physically damages the peptide structure, and this damage does not reverse when the solution thaws
doi: 10.1056/NEJMoa1905795 [PubMed] 32049893 Barra ME, Phillips KM, Chung DY, Rosenthal ES
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