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These findings indicate that changes in the levels of metabolites produced by the gut microbiota under atherosclerotic conditions may weaken the stability of atherosclerotic plaques and worsen the advancement of atherosclerosis (Shen et al., 2021)

DMP: Differentially methylated position

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Dual agonists target both the GLP-1R and another specific receptor, such as GIP (glucose-dependent insulinotropic polypeptide) or IGF (insulin-like growth factor) receptors

BMJ 374:n1648 Cysique LA, Jakabek D, Bracken SG, Allen-Davidian Y, Heng B, Chow S, Dehhaghi M, Pires AS, Darley DR, Byrne A, Phetsouphanh C, Kelleher A, Dore GJ, Matthews GV, Guillemin GJ, Brew BJ (2022) Post-acute Covid-19 cognitive impairment and decline uniquely associate with kynurenine pathway activation: a longitudinal observational study