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[42] Retinoids mediate their effect through important embryonic pathways such as transforming growth factor/fibroblast growth factor /hedgehog/wingless-type protein (TGF/FGF/Hh/Wnt) to ensure lung development in the uterus and to prevent premature birth and maternal anemia

United Eur Gastroenterol J 4:546561

Murdocca M, De Masi C, Pucci S, Mango R, Novelli G, Di Natale C et al (2021) LOX-1 and cancer, an indissoluble liaison

The treatment is typically repeated weekly or bi-weekly for optimal results, with many patients noticing improved skin radiance and overall wellness after just a few sessions