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One clinical trial gives a clearer picture of how often these side effects showed up at higher doses: Dysesthesia refers to unusual or unpleasant skin sensationsthings like tingling, burning, prickling, or a feeling that skin is overly sensitive to touch, sometimes described as a sunburned feeling without any visible cause

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At the end of the study, fasting blood glucose and insulin levels were measured following a 6-h fast, and HOMA-IR and HOMA- scores were calculated using standard formulas

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