Furthermore, owing to its narrow therapeutic index and large PK/PD variability, administering an initial busulfan IV dose based only on body weight (WT) may result in failure to reach the target therapeutic window (Ben Hassine et al., 2021
Th1 cells are involved in cell-mediated immunity, whereas Th2 cells participate in antibody-mediated immunity
Sites should be equipped with emergency supplies, and the staff must be well-prepared to handle medical emergencies
and (iii) altered ovarian morphology, involving increased follicle counts and ovarian volume (PCOM), though these findings must be interpreted with caution in adolescent and young adult populations
The term CHE was retained to avoid confusion from repeated nomenclature changes, to define OHE as West Haven grade II for clinical consistency, and because the distinction between MHE and grade I HE is difficult, and much of the existing literature applies to both [4]