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Early improvements in skin hydration, radiance, and tone can appear within 34 weeks

Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation [7]

If you dont notice any improvement and you were not deficient to begin with, it could mean your vitamin levels were adequate and the injection is simply maintaining that status

The body tries to heal, but the constant strain creates a vicious cycle of incomplete repair, leading to pain, stiffness, and a catastrophic loss of function

Last reviewed: May 27, 2026 Last updated: May 27, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations