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Body weight trajectories ( Figure 5I, J ) reveal that while daily TZP bolus caused noticeable weight loss in some animals, the hydrogel formulation promoted a more gradual and controlled weight reduction, consistent with improved tolerability and depot stability

Novo Nordisk will stop the once-weekly injectable semaglutide kidney outcomes trial, FLOW, based on interim analysis

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They analyzed electronic medical records of the University of Pennsylvania Health System between January 2022 and June 2025

The EEG analysis showed a reduction in Stage 1 (light) sleep and better sleep efficiency, with no evidence of pharmacological sedation