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Fsp1: A key regulator of ferroptosis

Humle K, Klanger B, Kolkhof P, et al

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Conclusions and perspectives UA induces oxidative stress, the inflammatory response in the -cells, and decreases GSIS, causing -cell apoptosis

Both drug therapies significantly reduced levels of oxidized glutathione (GSSG), 8-hydroxy-2-deoxyguanosine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA), while amlodipine also reduced 13-hydroxy octadecadienoic acid (13-HODE) levels