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Vaswani P, Kosra S, Kansara K, Kumar A, Bhatia D

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Nofreezing reconstituted peptides causes ice crystal formation that physically disrupts peptide structure and reduces bioactivity by 4060%

Psychiatry Investig 17:616626

In contrast to their expectations, the results have shown that daily supplementation with vitamin C and vitamin A for 4 weeks not only failed to improve the insulin responsiveness but also decreased the expression of ROS-sensitive transcriptional regulators, molecular mediators of ROS defense (SOD 1 and 2, glutathione peroxidase) [90]