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However, a pharmacovigilance study using the WHO's global adverse drug reaction database found disproportionate reporting of eating disorder adverse events with all three major GLP-1 medications ( Nishida et al., Clinical Nutrition, 2025 )

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Semaglutide dinyatakan memiliki profil keamanan yang baik dan bisa ditoleransi oleh pasien.[7] Perbandingan Semaglutide dan Liraglutide untuk Mengurangi Berat Badan pada Pasien Obesitas Tanpa Diabetes Mellitus Liraglutide merupakan agonis reseptor GLP-1 yang juga telah disetujui FDA sebagai terapi obesitas

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Additionally, women have unique safety considerations regarding pregnancy, as the FDA requires stopping Wegovy at least two months before trying to become pregnant due to potential risks to an unborn baby