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Inflammasomes, particularly the NLRP3 inflammasome, play a central role in regulating this phase by sensing both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) released during injury, such as those generated in thermal burns

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CJC-1295 No DAC's 49-fold potency enhancement over native GHRH arose from systematic -helix stabilization through strategic amino acid substitutions at positions 8, 9, and 15, combined with D-Ala substitution for proteolytic protection

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Sun, Y., Danser, A