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An interesting case is when measurements with similar metadata from different studies produce significantly different dynamics of metabolite concentrations, such as in the example of extracellular brain glucose from Kiyatkin and Lenoir (96) as compared with Fillenz and Lowry (97), which was further used in one of the early integrative NGV models ( Presentation 1: Supplementary Figure S17

The active factor was isolated and identified as this small peptide with a strong affinity for copper(II) ions

2014;3:CD005195

However, the underlying biochemical patterns remain unclear, and researchers continue to treat these outcomes cautiously

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