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In the context of obesity research, Adipotide has demonstrated the ability to cause rapid, significant weight loss in rhesus monkeys and rodents by literally destroying the tissue structure of fat deposits
[DOI] [PubMed] [Google Scholar] Qiu W
On the contrary, outside RCTs, subjects are never treated with placebo, and therefore RWS most of the time compared GLP-1RAs (or other drugs of interest) with an active comparator, thus yielding more clinically-relevant information
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