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But with rapid weight loss often comes unexpected changes in the skin: Loss of facial volume, sometimes called Ozempic face Increased skin laxity, especially along the jawline and cheeks Fine lines and wrinkles that appear more pronounced without underlying support A dull or tired look from reduced hydration and elasticity These changes can make patients feel like their appearance doesnt reflect how good they feel on the inside

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The most researched is GHK-Cu, a naturally occurring peptide that declines significantly with age