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Additional blood samples were treated with 1% Triton X-100 and 0.3% tributyl phosphate and incubated at 37C for 1 hour to destroy any virus

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In another in vitro and in vivo study, Nrf2/HO-1 was also demonstrated to play an important inhibitory role in the pro-fibrotic pathway activated by TGF-1, which was verified by oligo-fucoidan in NRK-52E cells and kidney tissues of C57BL/6 mice [151]

Funding This research was funded by Innovation Team Project of Dalian Ocean University, China (B202102) and the Central Guidance on Local Science and Technology Development Fund of Hebei Province (226Z7103G), China