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Because the body stores about 1,000 to 2,000 times as much as the typical daily intake of the vitamin, it can take several years to develop clinical symptoms of vitamin B12 deficiency

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All described studies evaluating small intestinal permeability used a 5 or 6 h urinary collection to assess small intestinal permeability, which may have confounded the results since a large amount of the sugars were probably already localized in the colon by the end of the urine collection (33)

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