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Dihexa induces spinogenesis in cultured hippocampal neurons Actin-enriched spines increased in number in response to both dihexa (Figure 38B&D) and Nle'-AnglV (Figure 38C&D) following 5 days of treatment at 10 "12 M concentration that started on the 7 th day in vitro (DIV7) the results revealed a near 3-fold increase in the number of spines stimulated by dihexa and greater than 2-fold increase for Nle f -AngIV

5% BSA was used to block nonspecific epitopes and then primary antibodies were incubated at 4 C overnight

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Retrieved May 3, 2025

Riedl MA, Nel AE: Importance of oxidative stress in the pathogenesis and treatment of asthma