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Intervention with retinoic acid (6 mg/kg for 21 days or 1 mg/kg for 10 days) significantly improved social functioning, as indicated by increased time spent in the social novelty chamber assessed by the three-chamber test
As mentioned previously, NRF2 regulates the expression of ATF4, which controls the expression of the glutamine transporter SLC1A5 [73], and asparagine synthetase (ASNS), which generates both asparagine and glutamate from aspartate and glutamine
