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Antioxidants 12(6):1199

ED-71 ameliorates bone regeneration in type 2 diabetes by reducing ferroptosis in osteoblasts via the HIF1alpha pathway

doi: 10.1016/j.jhep.2012.11.045 11 WalterSRTheinHHGiddingHFAminJLawMGGeorgeJet al

Many other nonenzymatic glutathionylations according to mechanism (ii) probably also have such small rate constants 63,86

They also suggest that glutathione supplementation may improve cardiac cell preservation in cardiac diseases, and be a complement to contemporary treatments