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Key takeaways Wegovy (semaglutide) is an injectable prescription weight loss medication for people 12 years and older

Patients using semaglutide typically see an average weight loss of 15% over 68 weeks, along with improved metabolic health, including better blood sugar control and cardiovascular benefits

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In the nucleus, FOXO4 activates the transcription of genes encoding antioxidant enzymes like manganese superoxide dismutase (MnSOD), catalase (CAT), and glutathione peroxidase (GPX)

Dehydration and renal function : Dehydration resulting from gastrointestinal side effects requires attention, as it can affect overall health, medication levels, and potentially lead to acute kidney injury, especially in those with pre-existing renal impairment