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There is reasonable scientific basis to expect that the GLP-1 component will confer similar cardiovascular protection

) Within the 10 4 -10 3 M range, however, the reduced Cu(I) form is minimally present, which would impair oxidative energy-transfer

The potential nephroprotective mechanisms of GLP-1RAs likely involve GLP-1RA-mediated improvements of conventional risk factors for diabetic kidney disease (control of glycaemia, postprandial lipid level, body weight and blood pressure), but perhaps also direct effects on the kidneys

PMID 16061918