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The mass spectroscopy was used for the identification of Jub B in the brain, and they revealed that significant amount of Jub B was present in the brain, it means that it can easily cross the BBB which is one the main barrier in the development of drugs against neurological disorders

GO and KEGG analyses demonstrated the enrichment of these DEGs in several ROS-related pathways, which are among the main mediators of ferroptosis

(1) IF induces p53-driven stress response pathways in adipocytes, subsequently altering the transcriptional profile of adipocytes

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Cytoprotective effects against viruses like SARS-CoV-2 could be enhanced by sulforaphane, an isothiocyanate abundant in cruciferous vegetables, since sulforaphane has been found to be a powerful activator of the Nrf2 pathway by increasing Nrf2-regulated cellular antioxidant response such as induction of NAD(P)H: quinone oxidoreductase 1, glutamate-cysteine ligase (-glutamyl cysteine synthetase) and glutathione (Theodore et al., 2008